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Search for "N-acylhomoserine lactones" in Full Text gives 5 result(s) in Beilstein Journal of Organic Chemistry.

Identification of volatiles from six marine Celeribacter strains

  • Anuj Kumar Chhalodia,
  • Jan Rinkel,
  • Dorota Konvalinkova,
  • Jörn Petersen and
  • Jeroen S. Dickschat

Beilstein J. Org. Chem. 2021, 17, 420–430, doi:10.3762/bjoc.17.38

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  • experiments also led to a suggestion for the mechanism for sulfur incorporation, but further research is required for a deep understanding of TDA biosynthesis. Besides its function as an antibiotic, TDA acts as a signaling molecule, similar to N-acylhomoserine lactones, at concentrations 100 times lower than
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Published 11 Feb 2021

N-Acylated amino acid methyl esters from marine Roseobacter group bacteria

  • Hilke Bruns,
  • Lisa Ziesche,
  • Nargis Khakin Taniwal,
  • Laura Wolter,
  • Thorsten Brinkhoff,
  • Jennifer Herrmann,
  • Rolf Müller and
  • Stefan Schulz

Beilstein J. Org. Chem. 2018, 14, 2964–2973, doi:10.3762/bjoc.14.276

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  • Roseobacter group (Rhodobacteraceae) are important members of many marine ecosystems. Similar to other Gram-negative bacteria many roseobacters produce N-acylhomoserine lactones (AHLs) for communication by quorum sensing systems. AHLs regulate different traits like cell differentiation or antibiotic
  • habitats with a broad metabolic potential [4][5][6][7]. Especially attached-living roseobacters produce diverse secondary metabolites, e.g., N-acylhomoserine lactones (AHLs) that the bacteria use for communication by quorum sensing [8][9][10]. AHLs are extensively investigated because of the broad
  • activity of the producing organism [29]. N-Acylhomoserine lactones 1 (Z7-C14:1-AHL) and N-acylalanine methyl esters 2 (Z9-C16:1-NAME) occurring in Roseobacter group bacteria. Total ion chromatogram (TIC) of an XAD extract of Roseovarius sp. D12_1.68. AHLs, NAMEs and related compounds are assigned by bold
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Published 03 Dec 2018

Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections

  • Matthew B. Calvert,
  • Varsha R. Jumde and
  • Alexander Titz

Beilstein J. Org. Chem. 2018, 14, 2607–2617, doi:10.3762/bjoc.14.239

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  • Gram-positive bacteria. While Gram-positive bacteria often use peptides as signal molecules, Gram-negative bacteria employ N-acylhomoserine lactones (AHLs) with subtle differences in their chemical structure, as well as other types of autoinducers (Figure 5). Interestingly, the signaling molecule
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Published 11 Oct 2018

Impact of Pseudomonas aeruginosa quorum sensing signaling molecules on adhesion and inflammatory markers in endothelial cells

  • Carmen Curutiu,
  • Florin Iordache,
  • Veronica Lazar,
  • Aurelia Magdalena Pisoschi,
  • Aneta Pop,
  • Mariana Carmen Chifiriuc and
  • Alina Maria Hoban

Beilstein J. Org. Chem. 2018, 14, 2580–2588, doi:10.3762/bjoc.14.235

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  • infections. P. aeruginosa produce two types of quorum-sensing signaling molecules (QSSMs): N-acylhomoserine lactones (AHL) and 2-alkyl-4-quinolone (PQS) derivatives. The AHLs molecules described so far in P. aeruginosa belong at two quorum sensing (QS) systems: las and rhl systems whose autoinducer (AI
  • of the disease. Recent studies have found that the QS molecules interact with eukaryotic cells and modulate also host immune response [9]. But, although the roles of the N-acylhomoserine lactones in the modulation of immune response have been well studied, the results obtained until now were
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Published 05 Oct 2018

Acyl-group specificity of AHL synthases involved in quorum-sensing in Roseobacter group bacteria

  • Lisa Ziesche,
  • Jan Rinkel,
  • Jeroen S. Dickschat and
  • Stefan Schulz

Beilstein J. Org. Chem. 2018, 14, 1309–1316, doi:10.3762/bjoc.14.112

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  • /bjoc.14.112 Abstract N-Acylhomoserine lactones (AHLs) are important bacterial messengers, mediating different bacterial traits by quorum sensing in a cell-density dependent manner. AHLs are also produced by many bacteria of the marine Roseobacter group, which constitutes a large group within the marine
  • ; fatty acid composition; N-acylhomoserine lactones; quorum sensing; Phaeobacter inhibens; Introduction The Roseobacter group, a subgroup of the Rhodobacteraceae family, constitutes an important class of Gram-negative marine bacteria, occurring in many different habitats [1][2], in fresh water as well as
  • on surfaces [3]. They can produce a variety of secondary metabolites, including antibiotics [4][5], volatile compounds [6][7], oligohydroxybutyrates [8] and a range of N-acylhomoserine lactones (AHLs) [8][9][10]. AHLs are quorum-sensing signaling compounds that are used for cell–cell communication to
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Published 05 Jun 2018
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